STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APH_0096Tim44-like domain protein; Identified by match to protein family HMM PF04280. (241 aa)    
Predicted Functional Partners:
APH_0062
Conserved hypothetical protein; Identified by similarity to GB:AAL02641.1; match to protein family HMM PF06242.
  
     0.740
APH_0775
Conserved hypothetical protein; Identified by similarity to PIR:E97838; match to protein family HMM PF07031.
  
     0.715
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
     0.710
secB
Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
 
     0.709
APH_0923
Disulfide bond formation protein, DsbB family; Identified by match to protein family HMM PF02600.
  
     0.699
APH_0849
Conserved hypothetical protein; Identified by similarity to GB:AAS14586.1.
  
     0.608
yidC
Inner membrane protein, 60 kDa; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
     0.508
lysS
lysyl-tRNA synthetase; Identified by similarity to SP:O27585; match to protein family HMM PF01921; match to protein family HMM TIGR00467; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
     0.501
APH_0976
Conserved hypothetical protein; Identified by similarity to GB:AAS14420.1.
  
     0.467
APH_1218
DNA-binding protein; Identified by similarity to GB:AAN15209.1; match to protein family HMM PF01381.
  
     0.464
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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