Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
APH_0122Thiol:disulfide oxidoreductase; Identified by similarity to GB:AAM22615.1; match to protein family HMM PF01323. (248 aa)    
Predicted Functional Partners:
APH_1213
Thiol:disulfide interchange protein, truncated; Identified by similarity to GB:AAM35423.1.
 
 
 0.903
APH_0923
Disulfide bond formation protein, DsbB family; Identified by match to protein family HMM PF02600.
 
 
 0.826
APH_0098
Conserved hypothetical protein; Identified by similarity to GB:AAS14712.1.
  
     0.711
APH_0378
Identified by similarity to GB:AAS14953.1; match to protein family HMM TIGR02217.
 
      0.683
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.559
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
    
 
 0.502
ctaA
Putative cytochrome oxidase assembly protein; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily.
 
    0.496
rpoH
RNA polymerase sigma-32 factor; Identified by similarity to SP:P48194; match to protein family HMM PF04542; match to protein family HMM PF04545; Belongs to the sigma-70 factor family.
 
   
 0.413
APH_0074
Conserved hypothetical protein; Identified by similarity to GB:AAS14910.1.
 
 
 
 0.402
APH_0545
heme/FAD-binding domain protein; Identified by similarity to GB:CAD84769.1; match to protein family HMM PF00175; match to protein family HMM PF00970.
 
   
 0.402
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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