STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
APH_0141Putative thiol:disulfide oxidoreductase; Identified by similarity to SP:P33926. (166 aa)    
Predicted Functional Partners:
APH_1271
Cytochrome c-type biogenesis protein, CcmF/CycK/CcsA family; Identified by similarity to SP:P45403; match to protein family HMM PF01578.
 
  
 0.959
ccmC
Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
  
 0.917
APH_0687
Cytochrome c biogenesis family protein; Possible subunit of a heme lyase.
 
  
 0.912
ccmE
Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
  
 0.908
APH_1213
Thiol:disulfide interchange protein, truncated; Identified by similarity to GB:AAM35423.1.
  
 
 0.889
APH_0659
Antioxidant, AhpC/Tsa family; Identified by match to protein family HMM PF00578.
  
 0.887
APH_1204
Cytochrome c-type biogenesis protein, truncated; Identified by similarity to SP:P45403.
 
  
 0.863
APH_1397
Putative heme exporter protein CcmB.
 
  
 0.861
msp5
Major surface protein 5; Identified by similarity to PIR:A49213; match to protein family HMM PF02630.
  
 
 0.750
APH_1084
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
    
 
 0.742
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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