Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
glpXFructose-1,6-bisphosphatase, class II; Identified by match to protein family HMM PF03320; match to protein family HMM TIGR00330. (311 aa)    
Predicted Functional Partners:
APH_0268
Transketolase, thiamine diphosphate binding domain, N-terminal fragment; Matched to N-terminus of full length Tkt (660 aa). Peptides match to this protein was detected in human HL-60 cells by global proteomic analysis.
   
 0.961
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 0.944
APH_0492
Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
    
 0.943
fba
Fructose-bisphosphate aldolase, class I; Identified by similarity to SP:P71295; match to protein family HMM PF01791.
     
 0.902
APH_0221
Putative lipoprotein NlpD; Identified by similarity to SP:P33648; match to protein family HMM PF01551.
      0.860
leuS
leucyl-tRNA synthetase; Identified by similarity to SP:P56457; match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
    0.658
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
    
 
 0.543
tpiA
Triosephosphate isomerase; Identified by similarity to SP:P04790; match to protein family HMM PF00121; match to protein family HMM TIGR00419.
     
 0.532
pgk
Phosphoglycerate kinase; Identified by similarity to SP:P09404; match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family.
     
 0.527
APH_0042
Malate dehydrogenase; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949.
   
  
 0.490
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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