STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APH_0260SPFH domain/band 7 family protein; Identified by match to protein family HMM PF01145. (284 aa)    
Predicted Functional Partners:
APH_1040
Putative cell division protein, degenerate; Likely degenerated ORF. Peptides match to this protein were not detected by global proteomic analysis.
   
 0.912
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.912
APH_0480
Conserved hypothetical protein TIGR01033; Identified by similarity to GB:AAS14201.1; match to protein family HMM PF01709; match to protein family HMM TIGR01033.
 
 
    0.739
APH_0101
Peptidase, M16 family; Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; Belongs to the peptidase M16 family.
  
 0.632
APH_1158
Peptidase, M16 family; Identified by match to protein family HMM PF00675; match to protein family HMM PF05193.
  
 0.632
APH_1159
Peptidase, M16 family; Identified by match to protein family HMM PF00675; match to protein family HMM PF05193.
  
 0.632
APH_0259
Ankyrin repeat protein; Identified by match to protein family HMM PF00023.
   
  0.587
sucB
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM TIGR01347.
   
  0.472
APH_1257
Putative pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
  0.472
APH_1084
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
   
   0.430
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.