Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pstBPhosphate ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; Belongs to the ABC transporter superfamily. (252 aa)    
Predicted Functional Partners:
pstA
Phosphate ABC transporter, permease protein PtsA; Identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974.
 0.999
pstC
Phosphate ABC transporter, permease protein PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 0.999
APH_1050
Putative phosphate ABC transporter, periplasmic phosphate-binding protein.
  
 0.996
APH_0256
Type I secretion system ATPase/hypothetical protein; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR01842.
 
      0.886
APH_0312
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.556
ctrA
DNA-binding response regulator CtrA; Name change according to the cited literature. PMID: 16882029.
     
 0.504
cckA
Sensor histidine kinase/response regulator CckA; Name change according to the cited literature. PMID: 16882029.
  
  
 0.501
APH_0129
tubulin/FtsZ family, C-terminal domain protein; Identified by match to protein family HMM PF03953.
   
 
 0.422
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.422
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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