Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pleDResponse regulator/GGDEF domain protein PleD; Name change according to the cited literature. PMID: 16882029. (456 aa)    
Predicted Functional Partners:
pleC
Sensor histidine kinase PleC; Name change according to the cited literature. PMID: 16882029.
 0.999
cckA
Sensor histidine kinase/response regulator CckA; Name change according to the cited literature. PMID: 16882029.
 
 0.966
APH_0553
Identified by match to protein family HMM PF05088.
    
 0.769
nrdB
Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
 
      0.756
ctrA
DNA-binding response regulator CtrA; Name change according to the cited literature. PMID: 16882029.
  
0.705
APH_0552
Putative twin-arginine translocation protein TatB; Identified by similarity to SP:O69415; match to protein family HMM PF02416.
       0.580
APH_0976
Conserved hypothetical protein; Identified by similarity to GB:AAS14420.1.
  
  
 0.579
ntrY
Nitrogen regulation protein/Sensor Histidine Kinase NtrY; Name change according to the cited literature. PMID: 16882029.
     
 0.494
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.459
APH_1170
Identified by match to protein family HMM PF00805.
  
     0.453
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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