STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APH_0659Antioxidant, AhpC/Tsa family; Identified by match to protein family HMM PF00578. (203 aa)    
Predicted Functional Partners:
trxB
Thioredoxin-disulfide reductase; Identified by similarity to SP:P09625; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292.
  
 
 0.966
APH_0141
Putative thiol:disulfide oxidoreductase; Identified by similarity to SP:P33926.
  
 0.887
APH_0561
Putative thiol-disulfide oxidoreductase; Identified by similarity to SP:P35160.
  
 0.887
APH_1280
Hypothetical protein; Identified by Glimmer2; putative.
  
 0.863
APH_0734
Pyridine nucleotide-disulfide oxidoreductase family protein; Identified by match to protein family HMM PF00070; match to protein family HMM PF03486; match to protein family HMM PF07992.
  
 
 0.838
trx
Thioredoxin; Identified by similarity to SP:P00274; match to protein family HMM PF00085; match to protein family HMM TIGR01068; Belongs to the thioredoxin family.
  
 
 0.828
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.794
hscA
Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
   
 
 0.794
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 0.705
sodB
Fe superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.704
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.