STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
putAProline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1045 aa)    
Predicted Functional Partners:
glnA
Glutamine synthetase, type I; Identified by similarity to SP:P05457; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653; Belongs to the glutamine synthetase family.
   
 
 0.961
aspC
Aspartate aminotransferase; Identified by similarity to SP:Q02635; match to protein family HMM PF00155.
   
 
 0.948
APH_1061
Glutamine synthetase domain protein; Identified by similarity to SP:P78061; match to protein family HMM PF00120; Belongs to the glutamine synthetase family.
   
 
 0.946
APH_0553
Identified by match to protein family HMM PF05088.
  
  
 0.936
APH_0225
Putative phosphoribosylformylglycinamidine synthase I; Identified by similarity to SP:P15254.
    
  0.901
gltX-1
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
    
  0.829
gltX-2
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
    
  0.829
lpdA-1
Dihydrolipoamide dehydrogenase; Identified by similarity to SP:P54533; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.
  
 
 0.816
lpdA-2
Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350.
  
 
 0.816
gshA
Glutamate--cysteine ligase; Identified by similarity to GB:AAB41630.1; match to protein family HMM TIGR02049.
     
 0.800
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.