APH_0679 protein (Anaplasma phagocytophilum)

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Score

APH_0679

Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF00111. (116 aa)

Predicted Functional Partners:

iscU

0.997

APH_0673

0.985

iscS

0.981

hscB

0.979

APH_0545

0.976

APH_0676

0.969

APH_0977

0.937

acpP

0.918

hscA

0.897

ctaA

0.890

Your Current Organism:

Anaplasma phagocytophilum

NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APH_0545	APH_0673	APH_0545	APH_0673	heme/FAD-binding domain protein; Identified by similarity to GB:CAD84769.1; match to protein family HMM PF00175; match to protein family HMM PF00970.	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	0.643
APH_0545	APH_0679	APH_0545	APH_0679	heme/FAD-binding domain protein; Identified by similarity to GB:CAD84769.1; match to protein family HMM PF00175; match to protein family HMM PF00970.	Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF00111.	0.976
APH_0545	hscA	APH_0545	APH_0678	heme/FAD-binding domain protein; Identified by similarity to GB:CAD84769.1; match to protein family HMM PF00175; match to protein family HMM PF00970.	Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.	0.467
APH_0545	iscS	APH_0545	APH_0674	heme/FAD-binding domain protein; Identified by similarity to GB:CAD84769.1; match to protein family HMM PF00175; match to protein family HMM PF00970.	Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.	0.427
APH_0545	iscU	APH_0545	APH_0675	heme/FAD-binding domain protein; Identified by similarity to GB:CAD84769.1; match to protein family HMM PF00175; match to protein family HMM PF00970.	FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.	0.470
APH_0673	APH_0545	APH_0673	APH_0545	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	heme/FAD-binding domain protein; Identified by similarity to GB:CAD84769.1; match to protein family HMM PF00175; match to protein family HMM PF00970.	0.643
APH_0673	APH_0676	APH_0673	APH_0676	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	Iron-sulfur cluster assembly accessory protein; Identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; Belongs to the HesB/IscA family.	0.968
APH_0673	APH_0679	APH_0673	APH_0679	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF00111.	0.985
APH_0673	APH_0977	APH_0673	APH_0977	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	Conserved hypothetical protein.	0.852
APH_0673	acpP	APH_0673	APH_0929	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	Putative acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.	0.841
APH_0673	hscA	APH_0673	APH_0678	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.	0.885
APH_0673	hscB	APH_0673	APH_0677	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	Co-chaperone protein hscB; Identified by similarity to SP:P36540; match to protein family HMM PF00226.	0.980
APH_0673	iscS	APH_0673	APH_0674	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.	0.996
APH_0673	iscU	APH_0673	APH_0675	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.	0.999
APH_0676	APH_0673	APH_0676	APH_0673	Iron-sulfur cluster assembly accessory protein; Identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; Belongs to the HesB/IscA family.	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	0.968
APH_0676	APH_0679	APH_0676	APH_0679	Iron-sulfur cluster assembly accessory protein; Identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; Belongs to the HesB/IscA family.	Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF00111.	0.969
APH_0676	APH_0977	APH_0676	APH_0977	Iron-sulfur cluster assembly accessory protein; Identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; Belongs to the HesB/IscA family.	Conserved hypothetical protein.	0.628
APH_0676	hscA	APH_0676	APH_0678	Iron-sulfur cluster assembly accessory protein; Identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; Belongs to the HesB/IscA family.	Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.	0.916
APH_0676	hscB	APH_0676	APH_0677	Iron-sulfur cluster assembly accessory protein; Identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; Belongs to the HesB/IscA family.	Co-chaperone protein hscB; Identified by similarity to SP:P36540; match to protein family HMM PF00226.	0.986
APH_0676	iscS	APH_0676	APH_0674	Iron-sulfur cluster assembly accessory protein; Identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; Belongs to the HesB/IscA family.	Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.	0.975