STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APH_0761Phage uncharacterized protein; Identified by match to protein family HMM TIGR01630. (445 aa)    
Predicted Functional Partners:
APH_0634
Phage conserved hypothetical protein, phiE125 gp8 family; Identified by match to protein family HMM TIGR02215.
 
   
 0.755
APH_0760
Hypothetical protein; Identified by Glimmer2; putative.
       0.631
APH_0688
Phage conserved hypothetical protein BR0599; Identified by match to protein family HMM TIGR02218.
 
     0.550
APH_0615
Hypothetical protein; Identified by Glimmer2; putative.
     
 0.538
APH_0641
Hypothetical protein; Identified by Glimmer2; putative.
     
 0.538
APH_0636
Conserved hypothetical protein; Identified by similarity to GB:AAS13839.1.
     
 0.489
APH_0635
Hypothetical protein; Identified by Glimmer2; putative.
     
 0.476
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      
 0.433
APH_0051
Iron-binding protein; Identified by similarity to GB:AAD03802.1; match to protein family HMM PF01547.
      
 0.428
APH_0378
Identified by similarity to GB:AAS14953.1; match to protein family HMM TIGR02217.
 
     0.428
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.