APH_0860 protein (Anaplasma phagocytophilum)

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Score

APH_0860

HIT family protein; Identified by match to protein family HMM PF01230. (124 aa)

Predicted Functional Partners:

ats-1

0.815

rpoC

0.771

rpoZ

0.763

rpoA

0.762

rpoB

0.753

APH_0858

0.572

APH_0545

0.525

APH_0673

0.480

mutS

0.457

grpE

0.452

Your Current Organism:

Anaplasma phagocytophilum

NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APH_0545	APH_0673	APH_0545	APH_0673	heme/FAD-binding domain protein; Identified by similarity to GB:CAD84769.1; match to protein family HMM PF00175; match to protein family HMM PF00970.	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	0.644
APH_0545	APH_0860	APH_0545	APH_0860	heme/FAD-binding domain protein; Identified by similarity to GB:CAD84769.1; match to protein family HMM PF00175; match to protein family HMM PF00970.	HIT family protein; Identified by match to protein family HMM PF01230.	0.525
APH_0545	grpE	APH_0545	APH_0036	heme/FAD-binding domain protein; Identified by similarity to GB:CAD84769.1; match to protein family HMM PF00175; match to protein family HMM PF00970.	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	0.453
APH_0545	rpoA	APH_0545	APH_0303	heme/FAD-binding domain protein; Identified by similarity to GB:CAD84769.1; match to protein family HMM PF00175; match to protein family HMM PF00970.	DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.431
APH_0545	rpoC	APH_0545	APH_1023	heme/FAD-binding domain protein; Identified by similarity to GB:CAD84769.1; match to protein family HMM PF00175; match to protein family HMM PF00970.	DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.484
APH_0545	rpoZ	APH_0545	APH_0514	heme/FAD-binding domain protein; Identified by similarity to GB:CAD84769.1; match to protein family HMM PF00175; match to protein family HMM PF00970.	DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.597
APH_0673	APH_0545	APH_0673	APH_0545	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	heme/FAD-binding domain protein; Identified by similarity to GB:CAD84769.1; match to protein family HMM PF00175; match to protein family HMM PF00970.	0.644
APH_0673	APH_0860	APH_0673	APH_0860	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	HIT family protein; Identified by match to protein family HMM PF01230.	0.480
APH_0673	grpE	APH_0673	APH_0036	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	0.570
APH_0673	rpoA	APH_0673	APH_0303	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.462
APH_0858	APH_0860	APH_0858	APH_0860	Hypothetical protein; Identified by Glimmer2; putative.	HIT family protein; Identified by match to protein family HMM PF01230.	0.572
APH_0858	ats-1	APH_0858	APH_0859	Hypothetical protein; Identified by Glimmer2; putative.	Anaplasma Translocated Substrate 1 (Ats-1); Name change according to the cited literature and GenBank accession number FJ210653. Edited start site from 912788 to 912419. PMID: 20174550.	0.572
APH_0858	mutS	APH_0858	APH_0857	Hypothetical protein; Identified by Glimmer2; putative.	DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.	0.480
APH_0860	APH_0545	APH_0860	APH_0545	HIT family protein; Identified by match to protein family HMM PF01230.	heme/FAD-binding domain protein; Identified by similarity to GB:CAD84769.1; match to protein family HMM PF00175; match to protein family HMM PF00970.	0.525
APH_0860	APH_0673	APH_0860	APH_0673	HIT family protein; Identified by match to protein family HMM PF01230.	Rrf2 family protein /cysteine desulfurase; Identified by similarity to GB:AAL10759.1; match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF02082.	0.480
APH_0860	APH_0858	APH_0860	APH_0858	HIT family protein; Identified by match to protein family HMM PF01230.	Hypothetical protein; Identified by Glimmer2; putative.	0.572
APH_0860	ats-1	APH_0860	APH_0859	HIT family protein; Identified by match to protein family HMM PF01230.	Anaplasma Translocated Substrate 1 (Ats-1); Name change according to the cited literature and GenBank accession number FJ210653. Edited start site from 912788 to 912419. PMID: 20174550.	0.815
APH_0860	grpE	APH_0860	APH_0036	HIT family protein; Identified by match to protein family HMM PF01230.	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	0.452
APH_0860	mutS	APH_0860	APH_0857	HIT family protein; Identified by match to protein family HMM PF01230.	DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.	0.457
APH_0860	rpoA	APH_0860	APH_0303	HIT family protein; Identified by match to protein family HMM PF01230.	DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.762