Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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APH_0933Putative DNA processing protein DprA; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. (344 aa)    
Predicted Functional Partners:
APH_0754
Magnesium chelatase, subunit D/I family, ComM subfamily; Identified by match to protein family HMM PF01078; match to protein family HMM TIGR00368.
 
 0.917
APH_1303
comF family protein.
 
 
 0.883
APH_0306
Identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360.
 
  
 0.877
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.796
ssb
Single-strand binding protein; Identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621.
  
  
 0.518
radC
DNA repair protein RadC; Identified by similarity to SP:P25531; match to protein family HMM PF04002; match to protein family HMM TIGR00608; Belongs to the UPF0758 family.
   
  
 0.513
APH_1223
recA protein, truncated; Identified by similarity to SP:Q04761.
   
 
 0.463
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 
 0.463
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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