STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APH_0955Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family. (835 aa)    
Predicted Functional Partners:
APH_0195
Cell division protein FtsQ; Identified by match to protein family HMM PF03799.
   
 
 0.820
APH_1036
Metallo-beta-lactamase family, beta-CASP subfamily; Identified by match to protein family HMM PF00753; match to protein family HMM PF07521.
 
    0.726
APH_0385
HGE-14 protein; Identified by similarity to GB:AAK69700.1.
    
 
 0.689
APH_0386
HGE-14 protein; Identified by similarity to GB:AAK69700.1.
    
 
 0.689
APH_0387
HGE-14 protein; Identified by similarity to GB:AAK69700.1.
    
 
 0.689
APH_0441
Hypothetical protein; Identified by Glimmer2; putative.
    
 
 0.689
APH_0455
HGE-14 protein; Identified by similarity to GB:AAK69700.1.
    
 
 0.689
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.669
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.547
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.545
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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