STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APH_1037TolB family protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (435 aa)    
Predicted Functional Partners:
APH_0338
OmpA family protein; Identified by similarity to SP:P07176; match to protein family HMM PF00691.
 
 
 0.989
APH_1036
Metallo-beta-lactamase family, beta-CASP subfamily; Identified by match to protein family HMM PF00753; match to protein family HMM PF07521.
      0.932
tolQ
TolQ protein; Identified by similarity to SP:P05828; match to protein family HMM PF01618.
 
  
 0.859
APH_0941
TonB family protein.
  
 
 0.781
bamD
Putative competence lipoprotein ComL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
   
 0.642
cckA
Sensor histidine kinase/response regulator CckA; Name change according to the cited literature. PMID: 16882029.
 
   
 0.576
bamA
Outer membrane protein, OMP85 family; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
  
 0.567
APH_1341
Lipoprotein releasing system, transmembrane protein, LolC/E family; Identified by match to protein family HMM PF02687; match to protein family HMM TIGR02212.
  
  
 0.495
APH_0062
Conserved hypothetical protein; Identified by similarity to GB:AAL02641.1; match to protein family HMM PF06242.
 
     0.466
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
 
  
 0.455
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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