STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APH_1043Type I secretion membrane fusion protein, HlyD family; Identified by match to protein family HMM PF00529; match to protein family HMM TIGR01843. (509 aa)    
Predicted Functional Partners:
APH_1110
Outer membrane efflux protein; Identified by match to protein family HMM PF02321.
 
 
 0.980
APH_0256
Type I secretion system ATPase/hypothetical protein; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR01842.
  
 0.940
APH_1084
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
    
 0.791
ctaD
Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
 
      0.776
APH_0352
Conserved hypothetical protein; Identified by similarity to GB:AAS13980.1; match to protein family HMM TIGR02281.
  
     0.606
APH_0164
Bicyclomycin resistance protein; Identified by similarity to SP:P28246; match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00710.
  
 
 0.603
APH_0848
Major facilitator family transporter; Identified by match to protein family HMM PF00083.
  
 
 0.603
APH_0041
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
  
  
 0.530
APH_1042
Conserved hypothetical protein; Identified by similarity to GB:AAS14534.1; match to protein family HMM TIGR02396.
       0.529
cckA
Sensor histidine kinase/response regulator CckA; Name change according to the cited literature. PMID: 16882029.
     
 0.508
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.