STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APH_1148Identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; Belongs to the peptidase S1C family. (490 aa)    
Predicted Functional Partners:
hflK
HflK protein; HflC and HflK could encode or regulate a protease.
  
 
 0.856
lon
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
    
 0.855
hflC
HflC protein; HflC and HflK could regulate a protease.
  
 
 0.854
APH_0433
Conserved domain protein.
    
  0.838
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 
  0.799
APH_0325
Oxidoreductase, FAD-binding protein; Identified by match to protein family HMM PF01266.
   
 
  0.762
APH_0157
Putative ABC transporter, ATP-binding protein/permease protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664.
    
  0.720
cckA
Sensor histidine kinase/response regulator CckA; Name change according to the cited literature. PMID: 16882029.
  
  
 0.710
APH_0362
Ribosomal large subunit pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
      0.704
APH_0338
OmpA family protein; Identified by similarity to SP:P07176; match to protein family HMM PF00691.
 
 
 
 0.674
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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