STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recJsingle-stranded-DNA-specific exonuclease RecJ; Identified by similarity to SP:P21893; match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644. (585 aa)    
Predicted Functional Partners:
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
     
 0.790
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
     
 0.768
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
   
 
 0.743
recG
ATP-dependent DNA helicase RecG; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271.
     
 0.742
APH_0957
CBS/transporter associated domain protein; Identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471.
      0.738
pstA
Phosphate ABC transporter, permease protein PtsA; Identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974.
      0.728
ssb
Single-strand binding protein; Identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621.
   
 
 0.659
APH_0225
Putative phosphoribosylformylglycinamidine synthase I; Identified by similarity to SP:P15254.
      0.647
APH_0903
Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580.
 
  
 0.627
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
     
 0.608
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.