STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APH_1214Identified by match to protein family HMM PF00768; match to protein family HMM PF07943; Belongs to the peptidase S11 family. (386 aa)    
Predicted Functional Partners:
APH_0258
ATP-dependent DNA helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580.
      0.694
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.452
mreB
Rod shape-determining protein MreB; Identified by similarity to SP:Q01465; match to protein family HMM PF06723; match to protein family HMM TIGR00904.
 
  
 0.447
APH_0994
Conserved hypothetical protein; Identified by similarity to GB:AAS14796.1; Belongs to the DnaA family.
  
   0.434
APH_1216
polyA polymerase/tRNA nucleotidyltransferase family protein; Identified by similarity to SP:P42977; match to protein family HMM PF01743; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.405
p44-14
Encodes a full-length P44 outer membrane protein.
       0.404
APH_0955
Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family.
 
   
 0.403
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.