STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
APH_1218DNA-binding protein; Identified by similarity to GB:AAN15209.1; match to protein family HMM PF01381. (183 aa)    
Predicted Functional Partners:
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
  
 0.775
holA
DNA polymerase III, delta subunit; Identified by similarity to GB:AAS14093.1; match to protein family HMM PF06144.
  
     0.771
APH_0062
Conserved hypothetical protein; Identified by similarity to GB:AAL02641.1; match to protein family HMM PF06242.
  
     0.745
APH_0110
Acetamidase/formamidase family protein.
  
     0.679
APH_0775
Conserved hypothetical protein; Identified by similarity to PIR:E97838; match to protein family HMM PF07031.
  
     0.664
APH_0985
Putative lipoprotein.
  
     0.634
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
     0.494
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
       0.490
APH_0096
Tim44-like domain protein; Identified by match to protein family HMM PF04280.
  
     0.464
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.452
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.