APH_1223 protein (Anaplasma phagocytophilum)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

APH_1223

recA protein, truncated; Identified by similarity to SP:Q04761. (84 aa)

Predicted Functional Partners:

polA

0.997

topA

0.920

dnaN

0.903

APH_0720

0.868

acpP

0.852

APH_0903

0.850

APH_0351

0.771

APH_1222

0.732

cckA

0.631

pheT

0.597

Your Current Organism:

Anaplasma phagocytophilum

NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APH_0351	APH_0720	APH_0351	APH_0720	Conserved hypothetical protein; Identified by similarity to GB:AAS14435.1.	Hypothetical protein; Identified by Glimmer2; putative.	0.867
APH_0351	APH_0903	APH_0351	APH_0903	Conserved hypothetical protein; Identified by similarity to GB:AAS14435.1.	Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580.	0.506
APH_0351	APH_1223	APH_0351	APH_1223	Conserved hypothetical protein; Identified by similarity to GB:AAS14435.1.	recA protein, truncated; Identified by similarity to SP:Q04761.	0.771
APH_0351	dnaN	APH_0351	APH_1097	Conserved hypothetical protein; Identified by similarity to GB:AAS14435.1.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.999
APH_0351	polA	APH_0351	APH_0001	Conserved hypothetical protein; Identified by similarity to GB:AAS14435.1.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.999
APH_0351	topA	APH_0351	APH_0597	Conserved hypothetical protein; Identified by similarity to GB:AAS14435.1.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.792
APH_0720	APH_0351	APH_0720	APH_0351	Hypothetical protein; Identified by Glimmer2; putative.	Conserved hypothetical protein; Identified by similarity to GB:AAS14435.1.	0.867
APH_0720	APH_0903	APH_0720	APH_0903	Hypothetical protein; Identified by Glimmer2; putative.	Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580.	0.616
APH_0720	APH_1223	APH_0720	APH_1223	Hypothetical protein; Identified by Glimmer2; putative.	recA protein, truncated; Identified by similarity to SP:Q04761.	0.868
APH_0720	acpP	APH_0720	APH_0929	Hypothetical protein; Identified by Glimmer2; putative.	Putative acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.	0.746
APH_0720	dnaN	APH_0720	APH_1097	Hypothetical protein; Identified by Glimmer2; putative.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.772
APH_0720	polA	APH_0720	APH_0001	Hypothetical protein; Identified by Glimmer2; putative.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.985
APH_0720	topA	APH_0720	APH_0597	Hypothetical protein; Identified by Glimmer2; putative.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.937
APH_0903	APH_0351	APH_0903	APH_0351	Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580.	Conserved hypothetical protein; Identified by similarity to GB:AAS14435.1.	0.506
APH_0903	APH_0720	APH_0903	APH_0720	Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580.	Hypothetical protein; Identified by Glimmer2; putative.	0.616
APH_0903	APH_1223	APH_0903	APH_1223	Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580.	recA protein, truncated; Identified by similarity to SP:Q04761.	0.850
APH_0903	dnaN	APH_0903	APH_1097	Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.960
APH_0903	pheT	APH_0903	APH_0305	Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580.	phenylalanyl-tRNA synthetase, beta subunit; Identified by similarity to SP:P07395; match to protein family HMM PF01588; match to protein family HMM PF03147; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.	0.554
APH_0903	polA	APH_0903	APH_0001	Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.810
APH_0903	topA	APH_0903	APH_0597	Helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.826