Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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APH_1347Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the YbaB/EbfC family. (102 aa)    
Predicted Functional Partners:
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
  
 0.943
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
  
 0.913
APH_1346
Putative aspartate-semialdehyde dehydrogenase; Identified by match to protein family HMM PF01118; match to protein family HMM PF02774; Belongs to the aspartate-semialdehyde dehydrogenase family.
       0.799
APH_0783
Conserved domain protein.
  
  
 0.606
acpP
Putative acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
   
    0.579
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
    0.534
gap
Glyceraldehyde-3-phosphate dehydrogenase, type I; Identified by similarity to SP:O34425; match to protein family HMM PF00044; match to protein family HMM PF02800; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
       0.519
APH_1345
Putative membrane protein; Identified by match to protein family HMM PF01027; Belongs to the BI1 family.
       0.425
APH_1344
Conserved hypothetical protein TIGR00150; Identified by similarity to GB:AAL02551.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150.
       0.412
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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