virD4 protein (Anaplasma phagocytophilum) - STRING interaction network

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virD4

Type IV secretion system protein VirD4; Identified by similarity to GB:AAM00422.1; match to protein family HMM PF02534. (740 aa)

Predicted Functional Partners:

virB10

0.994

virB11

0.992

virB8-1

0.989

virB9-1

0.976

virB9-2

0.954

virB4-1

0.905

APH_0419

0.891

virB4-2

0.837

topA

0.807

APH_0256

0.724

Your Current Organism:

Anaplasma phagocytophilum

NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APH_0256	virB10	APH_0256	APH_1404	Type I secretion system ATPase/hypothetical protein; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR01842.	Type IV secretion system protein VirB10; Identified by similarity to GB:AAM00418.1; match to protein family HMM PF03743.	0.670
APH_0256	virB11	APH_0256	APH_1403	Type I secretion system ATPase/hypothetical protein; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR01842.	Type IV secretion system protein VirB11; Part of the Type IV secretion system. Belongs to the GSP E family.	0.722
APH_0256	virB8-1	APH_0256	APH_1406	Type I secretion system ATPase/hypothetical protein; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR01842.	Type IV secretion protein VirB8-1; Name change from VirB8-2 to VirB8-1. PMID: 20670295.	0.699
APH_0256	virB9-1	APH_0256	APH_1405	Type I secretion system ATPase/hypothetical protein; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR01842.	Type IV secretion system protein VirB9 (VirB9-1); Name change from VirB9-2 to VirB9-1. PMID: 20670295.	0.541
APH_0256	virD4	APH_0256	APH_1402	Type I secretion system ATPase/hypothetical protein; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR01842.	Type IV secretion system protein VirD4; Identified by similarity to GB:AAM00422.1; match to protein family HMM PF02534.	0.724
APH_0419	topA	APH_0419	APH_0597	Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.420
APH_0419	virB10	APH_0419	APH_1404	Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1.	Type IV secretion system protein VirB10; Identified by similarity to GB:AAM00418.1; match to protein family HMM PF03743.	0.989
APH_0419	virB11	APH_0419	APH_1403	Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1.	Type IV secretion system protein VirB11; Part of the Type IV secretion system. Belongs to the GSP E family.	0.783
APH_0419	virB8-1	APH_0419	APH_1406	Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1.	Type IV secretion protein VirB8-1; Name change from VirB8-2 to VirB8-1. PMID: 20670295.	0.988
APH_0419	virB9-1	APH_0419	APH_1405	Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1.	Type IV secretion system protein VirB9 (VirB9-1); Name change from VirB9-2 to VirB9-1. PMID: 20670295.	0.918
APH_0419	virB9-2	APH_0419	APH_0081	Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1.	Type IV secretion system protein VirB9-2; Name change from VirB9-1 to VirB9-2. PMID: 20670295.	0.946
APH_0419	virD4	APH_0419	APH_1402	Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1.	Type IV secretion system protein VirD4; Identified by similarity to GB:AAM00422.1; match to protein family HMM PF02534.	0.891
topA	APH_0419	APH_0597	APH_0419	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1.	0.420
topA	virB11	APH_0597	APH_1403	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	Type IV secretion system protein VirB11; Part of the Type IV secretion system. Belongs to the GSP E family.	0.681
topA	virB4-1	APH_0597	APH_0373	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	Type IV secretion system protein VirB4 (VirB4-1); Name change from VirB4-1 to VirB4-2. PMID: 20670295.	0.420
topA	virB9-2	APH_0597	APH_0081	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	Type IV secretion system protein VirB9-2; Name change from VirB9-1 to VirB9-2. PMID: 20670295.	0.646
topA	virD4	APH_0597	APH_1402	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	Type IV secretion system protein VirD4; Identified by similarity to GB:AAM00422.1; match to protein family HMM PF02534.	0.807
virB10	APH_0256	APH_1404	APH_0256	Type IV secretion system protein VirB10; Identified by similarity to GB:AAM00418.1; match to protein family HMM PF03743.	Type I secretion system ATPase/hypothetical protein; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR01842.	0.670
virB10	APH_0419	APH_1404	APH_0419	Type IV secretion system protein VirB10; Identified by similarity to GB:AAM00418.1; match to protein family HMM PF03743.	Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1.	0.989
virB10	virB11	APH_1404	APH_1403	Type IV secretion system protein VirB10; Identified by similarity to GB:AAM00418.1; match to protein family HMM PF03743.	Type IV secretion system protein VirB11; Part of the Type IV secretion system. Belongs to the GSP E family.	0.985

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