| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APH_0419 | topA | APH_0419 | APH_0597 | Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.529 |
| APH_0419 | virB10 | APH_0419 | APH_1404 | Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1. | Type IV secretion system protein VirB10; Identified by similarity to GB:AAM00418.1; match to protein family HMM PF03743. | 0.967 |
| APH_0419 | virB11 | APH_0419 | APH_1403 | Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1. | Type IV secretion system protein VirB11; Part of the Type IV secretion system. Belongs to the GSP E family. | 0.823 |
| APH_0419 | virB3 | APH_0419 | APH_0372 | Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1. | Type IV secretion system protein VirB3; Identified by similarity to GB:AAM00406.1; match to protein family HMM PF05101. | 0.958 |
| APH_0419 | virB8-1 | APH_0419 | APH_1406 | Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1. | Type IV secretion protein VirB8-1; Name change from VirB8-2 to VirB8-1. PMID: 20670295. | 0.988 |
| APH_0419 | virB9-1 | APH_0419 | APH_1405 | Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1. | Type IV secretion system protein VirB9 (VirB9-1); Name change from VirB9-2 to VirB9-1. PMID: 20670295. | 0.943 |
| APH_0419 | virB9-2 | APH_0419 | APH_0081 | Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1. | Type IV secretion system protein VirB9-2; Name change from VirB9-1 to VirB9-2. PMID: 20670295. | 0.962 |
| APH_0419 | virD4 | APH_0419 | APH_1402 | Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1. | Type IV secretion system protein VirD4; Identified by similarity to GB:AAM00422.1; match to protein family HMM PF02534. | 0.922 |
| topA | APH_0419 | APH_0597 | APH_0419 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1. | 0.529 |
| topA | virB10 | APH_0597 | APH_1404 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Type IV secretion system protein VirB10; Identified by similarity to GB:AAM00418.1; match to protein family HMM PF03743. | 0.585 |
| topA | virB11 | APH_0597 | APH_1403 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Type IV secretion system protein VirB11; Part of the Type IV secretion system. Belongs to the GSP E family. | 0.838 |
| topA | virB4-1 | APH_0597 | APH_0373 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Type IV secretion system protein VirB4 (VirB4-1); Name change from VirB4-1 to VirB4-2. PMID: 20670295. | 0.529 |
| topA | virB9-2 | APH_0597 | APH_0081 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Type IV secretion system protein VirB9-2; Name change from VirB9-1 to VirB9-2. PMID: 20670295. | 0.645 |
| topA | virD4 | APH_0597 | APH_1402 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Type IV secretion system protein VirD4; Identified by similarity to GB:AAM00422.1; match to protein family HMM PF02534. | 0.849 |
| virB10 | APH_0419 | APH_1404 | APH_0419 | Type IV secretion system protein VirB10; Identified by similarity to GB:AAM00418.1; match to protein family HMM PF03743. | Type IV secretion system protein VirB4, truncated; Identified by similarity to GB:AAM00407.1. | 0.967 |
| virB10 | topA | APH_1404 | APH_0597 | Type IV secretion system protein VirB10; Identified by similarity to GB:AAM00418.1; match to protein family HMM PF03743. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.585 |
| virB10 | virB11 | APH_1404 | APH_1403 | Type IV secretion system protein VirB10; Identified by similarity to GB:AAM00418.1; match to protein family HMM PF03743. | Type IV secretion system protein VirB11; Part of the Type IV secretion system. Belongs to the GSP E family. | 0.994 |
| virB10 | virB3 | APH_1404 | APH_0372 | Type IV secretion system protein VirB10; Identified by similarity to GB:AAM00418.1; match to protein family HMM PF03743. | Type IV secretion system protein VirB3; Identified by similarity to GB:AAM00406.1; match to protein family HMM PF05101. | 0.976 |
| virB10 | virB4-1 | APH_1404 | APH_0373 | Type IV secretion system protein VirB10; Identified by similarity to GB:AAM00418.1; match to protein family HMM PF03743. | Type IV secretion system protein VirB4 (VirB4-1); Name change from VirB4-1 to VirB4-2. PMID: 20670295. | 0.981 |
| virB10 | virB4-2 | APH_1404 | APH_1129 | Type IV secretion system protein VirB10; Identified by similarity to GB:AAM00418.1; match to protein family HMM PF03743. | Type IV secretion system protein VirB4-2; Name change from VirB4-1 to VirB4-2. PMID: 20670295. | 0.974 |