CTC_02027 protein (Clostridium tetani) - STRING interaction network

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Score

CTC_02027

Fe-S oxidoreductase. (433 aa)

Predicted Functional Partners:

prmA

0.949

CTC_02028

0.918

dnaJ

0.733

CTC_01222

0.714

CTC_02026

0.699

CTC_02034

0.583

dnaK-2

0.570

lepA-2

0.561

CTC_02025

0.533

rlmN

0.514

Your Current Organism:

Clostridium tetani

NCBI taxonomy Id: 212717
Other names: C. tetani E88, Clostridium tetani E88, Clostridium tetani str. E88

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTC_01222	CTC_02027	CTC_01222	CTC_02027	16S rRNA M(5)C 967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	Fe-S oxidoreductase.	0.714
CTC_01222	CTC_02028	CTC_01222	CTC_02028	16S rRNA M(5)C 967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	Conserved surface protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.	0.484
CTC_01222	dnaJ	CTC_01222	CTC_02030	16S rRNA M(5)C 967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.404
CTC_01222	lepA-2	CTC_01222	CTC_02035	16S rRNA M(5)C 967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.	0.482
CTC_01222	prmA	CTC_01222	CTC_02029	16S rRNA M(5)C 967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.	0.760
CTC_01222	rlmN	CTC_01222	CTC_01223	16S rRNA M(5)C 967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	Florfenicol resistance protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.	0.993
CTC_02025	CTC_02026	CTC_02025	CTC_02026	Conserved cytosolic protein.	Hit family protein.	0.598
CTC_02025	CTC_02027	CTC_02025	CTC_02027	Conserved cytosolic protein.	Fe-S oxidoreductase.	0.533
CTC_02025	CTC_02028	CTC_02025	CTC_02028	Conserved cytosolic protein.	Conserved surface protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.	0.555
CTC_02025	dnaJ	CTC_02025	CTC_02030	Conserved cytosolic protein.	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.462
CTC_02025	dnaK-2	CTC_02025	CTC_02031	Conserved cytosolic protein.	Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.443
CTC_02025	prmA	CTC_02025	CTC_02029	Conserved cytosolic protein.	Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.	0.590
CTC_02026	CTC_02025	CTC_02026	CTC_02025	Hit family protein.	Conserved cytosolic protein.	0.598
CTC_02026	CTC_02027	CTC_02026	CTC_02027	Hit family protein.	Fe-S oxidoreductase.	0.699
CTC_02026	CTC_02028	CTC_02026	CTC_02028	Hit family protein.	Conserved surface protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.	0.680
CTC_02026	dnaJ	CTC_02026	CTC_02030	Hit family protein.	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.591
CTC_02026	dnaK-2	CTC_02026	CTC_02031	Hit family protein.	Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.572
CTC_02026	lepA-2	CTC_02026	CTC_02035	Hit family protein.	GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.	0.448
CTC_02026	prmA	CTC_02026	CTC_02029	Hit family protein.	Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.	0.669
CTC_02027	CTC_01222	CTC_02027	CTC_01222	Fe-S oxidoreductase.	16S rRNA M(5)C 967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	0.714