Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB20715.1PFAM: Permease family. (470 aa)    
Predicted Functional Partners:
AGB20891.1
PFAM: Permease family; TIGRFAM: uracil-xanthine permease.
 
  
 0.824
apt
PRPP-binding protein, adenine/guanine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
  
 0.621
purN
Phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
  
 0.555
purD
Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family.
  
  
 0.536
AGB21423.1
PFAM: GMC oxidoreductase; TIGRFAM: dehydrogenase, Rv0697 family.
  
 0.525
AGB21551.1
Choline dehydrogenase-like flavoprotein; PFAM: GMC oxidoreductase.
  
 0.525
AGB23019.1
Choline dehydrogenase-like flavoprotein; PFAM: GMC oxidoreductase.
  
 0.525
AGB24028.1
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
  
 0.525
AGB24481.1
Choline dehydrogenase-like flavoprotein; PFAM: GMC oxidoreductase.
  
 0.525
AGB25008.1
Choline dehydrogenase-like flavoprotein; PFAM: GMC oxidoreductase.
  
 0.525
Your Current Organism:
Mycobacterium sp. JS623
NCBI taxonomy Id: 212767
Other names: M. sp. JS623
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