Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB21903.1PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (310 aa)    
Predicted Functional Partners:
AGB21908.1
Formate dehydrogenase alpha subunit; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: formate dehydrogenase, alpha subunit, archaeal-type.
 
   
 0.636
AGB21902.1
PAS domain S-box; PFAM: PAS fold; TIGRFAM: PAS domain S-box.
     
 0.567
AGB21904.1
oxalyl-CoA decarboxylase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: oxalyl-CoA decarboxylase; Belongs to the TPP enzyme family.
 
   
 0.565
AGB21909.1
PFAM: NADH-dependant formate dehydrogenase delta subunit FdsD.
 
   
 0.502
AGB21906.1
PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit.
 
   
 0.485
AGB21907.1
NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 51 Kd subunit.
 
   
 0.485
AGB22828.1
Mn-dependent transcriptional regulator; PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain.
  
 
 0.466
AGB21060.1
PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain; manually curated.
  
 
 0.437
AGB24594.1
cAMP-binding protein; PFAM: Cyclic nucleotide-binding domain.
  
 
 0.437
AGB26147.1
PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain.
  
 
 0.437
Your Current Organism:
Mycobacterium sp. JS623
NCBI taxonomy Id: 212767
Other names: M. sp. JS623
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