Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB22308.12-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; PFAM: Fumarylacetoacetate (FAA) hydrolase family. (328 aa)    
Predicted Functional Partners:
AGB22306.1
PFAM: Prolyl oligopeptidase family.
 
  
  0.853
AGB22307.1
Putative metal-dependent hydrolase; PFAM: Putative cyclase.
 
     0.833
AGB22295.1
Lactoylglutathione lyase-like lyase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.
 
   
 0.754
AGB21966.1
PFAM: homogentisate 1,2-dioxygenase.
 
 
 0.665
AGB22299.1
PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.631
AGB25056.1
2-oxoglutarate dehydrogenase E1 component; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component.
  
 
 0.590
AGB23121.1
PFAM: Protein of unknown function (DUF3237); Belongs to the UPF0311 family.
 
 
 0.584
AGB22728.1
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; PFAM: HpcH/HpaI aldolase/citrate lyase family; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.573
AGB22298.1
Dihydrodipicolinate synthase/N-acetylneuraminate lyase; PFAM: Dihydrodipicolinate synthetase family; Belongs to the DapA family.
 
   
 0.560
AGB20515.1
PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
  
 0.546
Your Current Organism:
Mycobacterium sp. JS623
NCBI taxonomy Id: 212767
Other names: M. sp. JS623
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