STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGB22414.1Fe2+/Zn2+ uptake regulation protein; PFAM: Ferric uptake regulator family; Belongs to the Fur family. (147 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.889
AGB22411.1
ATPase component of Mn/Zn ABC-type transporter; PFAM: ABC transporter.
  
  
 0.851
AGB22412.1
ABC-type Mn2+/Zn2+ transport system, permease component; PFAM: ABC 3 transport family.
  
  
 0.844
AGB22413.1
ABC-type Mn2+/Zn2+ transport system, permease component; PFAM: ABC 3 transport family.
  
  
 0.844
AGB22410.1
ABC-type metal ion transport system, periplasmic component/surface adhesin; PFAM: Periplasmic solute binding protein family.
  
  
 0.809
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.737
AGB22921.1
RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
 
 0.708
sigA
RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.708
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 0.674
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   0.659
Your Current Organism:
Mycobacterium sp. JS623
NCBI taxonomy Id: 212767
Other names: M. sp. JS623
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.