Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGB22527.1PFAM: Bacterial regulatory proteins, tetR family; manually curated. (246 aa)    
Predicted Functional Partners:
nrdI
Ribonucleoside-diphosphate reductase 2, operon protein nrdI; Probably involved in ribonucleotide reductase function.
  
    0.763
AGB22524.1
Ribonucleoside-diphosphate reductase class Ib alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
  
 0.694
AGB22522.1
Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit; PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein NrdH.
  
    0.611
AGB22526.1
PFAM: FAD binding domain; TIGRFAM: geranylgeranyl reductase family.
     
 0.553
AGB20655.1
Acyl dehydratase; PFAM: MaoC like domain.
 
   
 0.552
AGB21910.1
PFAM: HNH endonuclease; Domain of unknown function DUF222.
  
     0.509
AGB22865.1
Hypothetical protein.
  
     0.505
AGB25081.1
PFAM: Bacterial regulatory proteins, tetR family.
  
   
 0.502
AGB24087.1
Hypothetical protein.
  
     0.501
AGB24536.1
PFAM: Acyl-ACP thioesterase.
 
   
 0.501
Your Current Organism:
Mycobacterium sp. JS623
NCBI taxonomy Id: 212767
Other names: M. sp. JS623
Server load: medium (52%) [HD]