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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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[Homology]
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AGB22844.1Dienelactone hydrolase-like enzyme; PFAM: Dienelactone hydrolase family. (246 aa)    
Predicted Functional Partners:
AGB23649.1
Dienelactone hydrolase-like enzyme; PFAM: Dienelactone hydrolase family.
 
  
  0.942
AGB23978.1
Dienelactone hydrolase-like enzyme; PFAM: Dienelactone hydrolase family.
  
  
 
0.926
AGB22843.1
Hypothetical protein; Manually curated.
       0.773
AGB22847.1
PFAM: Protein of unknown function (DUF1006).
 
     0.752
AGB22846.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.733
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
 0.604
AGB22341.1
PFAM: Dioxygenase; Catechol dioxygenase N terminus; TIGRFAM: catechol 1,2-dioxygenase, Actinobacterial.
  
 
 0.495
AGB25681.1
PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 
 0.473
AGB23141.1
Penicillin-binding protein, beta-lactamase class C; PFAM: Beta-lactamase.
 
  
  0.441
AGB21307.1
PFAM: Luciferase-like monooxygenase; TIGRFAM: probable F420-dependent oxidoreductase, MSMEG_2256 family.
       0.437
Your Current Organism:
Mycobacterium sp. JS623
NCBI taxonomy Id: 212767
Other names: M. sp. JS623
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