Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB23828.1Transcriptional regulator; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; Belongs to the LysR transcriptional regulatory family. (316 aa)    
Predicted Functional Partners:
AGB23827.1
Putative permease, DMT superfamily; PFAM: EamA-like transporter family.
 
  
 0.690
AGB21520.1
PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; manually curated; Belongs to the LysR transcriptional regulatory family.
  
     0.497
AGB20726.1
PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; manually curated; non-canonical start codon; Belongs to the LysR transcriptional regulatory family.
  
     0.482
AGB23826.1
PFAM: Domain of unknown function (DUF385).
       0.479
AGB22828.1
Mn-dependent transcriptional regulator; PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain.
  
 
 0.466
AGB21060.1
PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain; manually curated.
  
 
 0.437
AGB24594.1
cAMP-binding protein; PFAM: Cyclic nucleotide-binding domain.
  
 
 0.437
AGB26147.1
PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain.
  
 
 0.437
AGB23168.1
ABC-type antimicrobial peptide transport system, ATPase component; PFAM: ABC transporter; Cyclic nucleotide-binding domain.
  
 
 0.415
AGB23614.1
PFAM: Mechanosensitive ion channel; Cyclic nucleotide-binding domain.
  
 
 0.413
Your Current Organism:
Mycobacterium sp. JS623
NCBI taxonomy Id: 212767
Other names: M. sp. JS623
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