Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGB24413.1Transcriptional regulator; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator. (276 aa)    
Predicted Functional Partners:
AGB24415.1
Hypothetical protein.
       0.861
AGB24416.1
PFAM: Stress responsive A/B Barrel Domain; manually curated.
       0.861
AGB24414.1
Esterase/lipase; PFAM: alpha/beta hydrolase fold.
  
    0.783
AGB24204.1
Biotin-dependent carboxylase-like protein; PFAM: Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1; TIGRFAM: urea carboxylase; biotin-dependent carboxylase uncharacterized domain.
  
  
 0.778
AGB24417.1
Hypothetical protein.
     
 0.775
AGB25006.1
Transcriptional regulator; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator.
  
     0.765
AGB25607.1
Transcriptional regulator; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator.
  
     0.689
AGB24411.1
2,3-dihydroxybiphenyl 1,2-dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 2,3-dihydroxybiphenyl 1,2-dioxygenase.
  
    0.651
AGB24412.1
Succinate dehydrogenase/fumarate reductase flavoprotein subunit; PFAM: FAD binding domain.
  
  
 0.641
AGB24410.1
PFAM: Acyl-CoA dehydrogenase, C-terminal domain.
       0.555
Your Current Organism:
Mycobacterium sp. JS623
NCBI taxonomy Id: 212767
Other names: M. sp. JS623
Server load: low (40%) [HD]