node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGB21246.1 | AGB24954.1 | Mycsm_00810 | Mycsm_04728 | Threonine dehydratase, medium form; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.979 |
AGB21246.1 | AGB24955.1 | Mycsm_00810 | Mycsm_04729 | Threonine dehydratase, medium form; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form. | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. | 0.621 |
AGB21246.1 | AGB26201.1 | Mycsm_00810 | Mycsm_06037 | Threonine dehydratase, medium form; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form. | PFAM: Amino acid kinase family; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. | 0.507 |
AGB21246.1 | AGB26239.1 | Mycsm_00810 | Mycsm_06079 | Threonine dehydratase, medium form; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form. | Threonine aldolase; PFAM: Beta-eliminating lyase. | 0.926 |
AGB21246.1 | ilvA | Mycsm_00810 | Mycsm_02940 | Threonine dehydratase, medium form; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.919 |
AGB21246.1 | thrB | Mycsm_00810 | Mycsm_04727 | Threonine dehydratase, medium form; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.567 |
AGB23695.1 | AGB24954.1 | Mycsm_03395 | Mycsm_04728 | Threonine dehydratase; PFAM: Pyridoxal-phosphate dependent enzyme. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.830 |
AGB23695.1 | AGB24955.1 | Mycsm_03395 | Mycsm_04729 | Threonine dehydratase; PFAM: Pyridoxal-phosphate dependent enzyme. | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. | 0.572 |
AGB23695.1 | AGB26201.1 | Mycsm_03395 | Mycsm_06037 | Threonine dehydratase; PFAM: Pyridoxal-phosphate dependent enzyme. | PFAM: Amino acid kinase family; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. | 0.507 |
AGB23695.1 | thrB | Mycsm_03395 | Mycsm_04727 | Threonine dehydratase; PFAM: Pyridoxal-phosphate dependent enzyme. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.567 |
AGB24954.1 | AGB21246.1 | Mycsm_04728 | Mycsm_00810 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Threonine dehydratase, medium form; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form. | 0.979 |
AGB24954.1 | AGB23695.1 | Mycsm_04728 | Mycsm_03395 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Threonine dehydratase; PFAM: Pyridoxal-phosphate dependent enzyme. | 0.830 |
AGB24954.1 | AGB24955.1 | Mycsm_04728 | Mycsm_04729 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. | 0.995 |
AGB24954.1 | AGB26201.1 | Mycsm_04728 | Mycsm_06037 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | PFAM: Amino acid kinase family; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. | 0.901 |
AGB24954.1 | AGB26239.1 | Mycsm_04728 | Mycsm_06079 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Threonine aldolase; PFAM: Beta-eliminating lyase. | 0.952 |
AGB24954.1 | argS | Mycsm_04728 | Mycsm_04731 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase. | 0.905 |
AGB24954.1 | ilvA | Mycsm_04728 | Mycsm_02940 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.980 |
AGB24954.1 | lysA | Mycsm_04728 | Mycsm_04730 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.885 |
AGB24954.1 | serC | Mycsm_04728 | Mycsm_05452 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.954 |
AGB24954.1 | thrB | Mycsm_04728 | Mycsm_04727 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.999 |