STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PV10_05066Uncharacterized protein. (611 aa)    
Predicted Functional Partners:
PV10_07476
Uncharacterized protein.
  
  
 0.765
B0A52_02140
Uncharacterized protein.
      
 0.623
NCS2
Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.
      
 0.600
PV10_06876
Dihydroorotate dehydrogenase (Fumarate).
  
  
 0.591
PV10_08308
DHO_dh domain-containing protein.
  
  
 0.591
PV10_04887
Protein pyrABCN.
  
  
 0.559
PV10_07250
Carbamoyl-phosphate synthase, large subunit.
  
  
 0.559
PV10_06169
Carbamoyl-phosphate synthase arginine-specific small chain, variant.
  
  
 0.559
PV10_03236
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family.
  
  
 0.544
PV10_07203
Orotate phosphoribosyltransferase.
  
  
 0.544
Your Current Organism:
Exophiala mesophila
NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila
Server load: low (28%) [HD]