| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| celC | tyrS | SCITRI_001353 | SCITRI_001743 | PTS system cellobiose-specific IIA component. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.696 |
| celC | upp | SCITRI_001353 | SCITRI_00145 | PTS system cellobiose-specific IIA component. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.771 |
| cmk | glyA | SCITRI_00424 | SCITRI_001840 | Cytidylate kinase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.554 |
| cmk | guaA | SCITRI_00424 | SCITRI_00386 | Cytidylate kinase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.454 |
| cmk | pyrH | SCITRI_00424 | SCITRI_00478 | Cytidylate kinase. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.525 |
| cmk | tdk | SCITRI_00424 | SCITRI_0056 | Cytidylate kinase. | Thymidine kinase. | 0.502 |
| cmk | upp | SCITRI_00424 | SCITRI_00145 | Cytidylate kinase. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.622 |
| deoA | deoD | SCITRI_00529 | SCITRI_00597 | Pyrimidine-nucleoside phosphorylase. | Purine nucleoside phosphorylase. | 0.987 |
| deoA | guaA | SCITRI_00529 | SCITRI_00386 | Pyrimidine-nucleoside phosphorylase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.456 |
| deoA | tdk | SCITRI_00529 | SCITRI_0056 | Pyrimidine-nucleoside phosphorylase. | Thymidine kinase. | 0.985 |
| deoA | upp | SCITRI_00529 | SCITRI_00145 | Pyrimidine-nucleoside phosphorylase. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.950 |
| deoD | deoA | SCITRI_00597 | SCITRI_00529 | Purine nucleoside phosphorylase. | Pyrimidine-nucleoside phosphorylase. | 0.987 |
| deoD | guaA | SCITRI_00597 | SCITRI_00386 | Purine nucleoside phosphorylase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.424 |
| deoD | tdk | SCITRI_00597 | SCITRI_0056 | Purine nucleoside phosphorylase. | Thymidine kinase. | 0.976 |
| deoD | upp | SCITRI_00597 | SCITRI_00145 | Purine nucleoside phosphorylase. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.911 |
| glyA | cmk | SCITRI_001840 | SCITRI_00424 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Cytidylate kinase. | 0.554 |
| glyA | guaA | SCITRI_001840 | SCITRI_00386 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.512 |
| glyA | pyrH | SCITRI_001840 | SCITRI_00478 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.537 |
| glyA | tdk | SCITRI_001840 | SCITRI_0056 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Thymidine kinase. | 0.562 |
| glyA | upp | SCITRI_001840 | SCITRI_00145 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.650 |