hprT protein (Spiroplasma citri) - STRING interaction network

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hprT

Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (174 aa)

Predicted Functional Partners:

guaA

0.991

purA

0.930

adk

0.930

gmk

0.930

hpt

0.920

rdgB

0.917

guaC

0.912

deoD

0.905

rnhB

0.754

apt

0.536

Your Current Organism:

Spiroplasma citri

NCBI taxonomy Id: 2133
Other names: ATCC 27556, NCPPB 2647, S. citri

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
adk	apt	SCITRI_00351	SCITRI_00786	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.948
adk	gmk	SCITRI_00351	SCITRI_00446	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.760
adk	guaA	SCITRI_00351	SCITRI_00386	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.602
adk	hprT	SCITRI_00351	SCITRI_00385	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.930
adk	purA	SCITRI_00351	SCITRI_00274	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.409
apt	adk	SCITRI_00786	SCITRI_00351	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.948
apt	deoD	SCITRI_00786	SCITRI_00597	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Purine nucleoside phosphorylase.	0.918
apt	gmk	SCITRI_00786	SCITRI_00446	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.611
apt	guaA	SCITRI_00786	SCITRI_00386	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.795
apt	guaC	SCITRI_00786	SCITRI_00580	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.	0.415
apt	hprT	SCITRI_00786	SCITRI_00385	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.536
apt	hpt	SCITRI_00786	SCITRI_001505	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Putative hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.446
apt	purA	SCITRI_00786	SCITRI_00274	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.764
deoD	apt	SCITRI_00597	SCITRI_00786	Purine nucleoside phosphorylase.	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.918
deoD	hprT	SCITRI_00597	SCITRI_00385	Purine nucleoside phosphorylase.	Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.905
deoD	hpt	SCITRI_00597	SCITRI_001505	Purine nucleoside phosphorylase.	Putative hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.905
gmk	adk	SCITRI_00446	SCITRI_00351	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.760
gmk	apt	SCITRI_00446	SCITRI_00786	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.611
gmk	guaA	SCITRI_00446	SCITRI_00386	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.964
gmk	guaC	SCITRI_00446	SCITRI_00580	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.	0.931