node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apt | gmk | SCITRI_00786 | SCITRI_00446 | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.967 |
apt | guaA | SCITRI_00786 | SCITRI_00386 | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.990 |
apt | guaC | SCITRI_00786 | SCITRI_00580 | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.941 |
apt | hprT | SCITRI_00786 | SCITRI_00385 | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.958 |
apt | hpt | SCITRI_00786 | SCITRI_001505 | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.945 |
apt | pyrG | SCITRI_00786 | SCITRI_00273 | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.416 |
argS | gmk | SCITRI_00448 | SCITRI_00446 | arginyl-tRNA synthetase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.756 |
argS | guaA | SCITRI_00448 | SCITRI_00386 | arginyl-tRNA synthetase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.916 |
argS | karS | SCITRI_00448 | SCITRI_0017 | arginyl-tRNA synthetase. | lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.976 |
argS | pyrG | SCITRI_00448 | SCITRI_00273 | arginyl-tRNA synthetase. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.537 |
gmk | apt | SCITRI_00446 | SCITRI_00786 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.967 |
gmk | argS | SCITRI_00446 | SCITRI_00448 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | arginyl-tRNA synthetase. | 0.756 |
gmk | guaA | SCITRI_00446 | SCITRI_00386 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.948 |
gmk | guaC | SCITRI_00446 | SCITRI_00580 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.934 |
gmk | hprT | SCITRI_00446 | SCITRI_00385 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.952 |
gmk | hpt | SCITRI_00446 | SCITRI_001505 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.932 |
gmk | pyrG | SCITRI_00446 | SCITRI_00273 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.648 |
gmk | rdgB | SCITRI_00446 | SCITRI_00584 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.561 |
guaA | apt | SCITRI_00386 | SCITRI_00786 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.990 |
guaA | argS | SCITRI_00386 | SCITRI_00448 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | arginyl-tRNA synthetase. | 0.916 |