STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pdhAPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (367 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 component subunit beta.
 0.999
lpdA
Pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase) component.
 
 0.999
pdhC
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.993
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 
 0.943
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.934
gpi
Glucose-6-phosphate isomerase.
    
 0.901
fbaA2
Fructose-bisphosphate aldolase.
  
 
 0.888
tkt
Transketolase; Belongs to the transketolase family.
  
 
 0.856
tkt-2
Putative transketolase; Belongs to the transketolase family.
  
 
 0.848
gapN
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.846
Your Current Organism:
Spiroplasma citri
NCBI taxonomy Id: 2133
Other names: ATCC 27556, NCPPB 2647, S. citri
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