STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (367 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 component subunit beta.
 0.999
lpdA
Pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase) component.
 
 0.999
pdhC
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 0.998
APE74310.1
Putative dihydrolipoamide acetyltransferase.
 
 0.963
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 
 0.951
APE74024.1
Hypothetical protein.
 
 0.948
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.936
lplA
Putative lipoate-protein ligase A.
  
 
 0.934
ldhA
D-lactate dehydrogenase.
  
 
 0.909
gpi
Glucose-6-phosphate isomerase.
    
 0.907
Your Current Organism:
Spiroplasma citri
NCBI taxonomy Id: 2133
Other names: ATCC 27556, NCPPB 2647, S. citri
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