Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
uppSUndecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (235 aa)    
Predicted Functional Partners:
cdsA
Phosphatidate cytidylyltransferase; Belongs to the CDS family.
 
  
 0.956
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
  
  
 0.925
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
 
  
 0.854
rseP
Inner membrane zinc metalloprotease.
 
  
 0.823
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.818
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.670
era
Putative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
  
 0.625
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
  
  
 0.612
polC
DNA polymerase III subunit alpha (PolC); Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
       0.611
nusA
Transcription elongation factor NusA; Participates in both transcription termination and antitermination.
  
    0.518
Your Current Organism:
Spiroplasma citri
NCBI taxonomy Id: 2133
Other names: ATCC 27556, NCPPB 2647, S. citri
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