polC protein (Spiroplasma citri) - STRING interaction network

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polC

DNA polymerase III subunit alpha (PolC); Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1453 aa)

Predicted Functional Partners:

dnaN

0.950

dnaX

0.944

holB

0.943

dnaE

0.938

holA

0.938

rseP

0.744

cdsA

0.684

yqfN

0.677

era

0.637

polA

0.624

Your Current Organism:

Spiroplasma citri

NCBI taxonomy Id: 2133
Other names: ATCC 27556, NCPPB 2647, S. citri

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cdsA	era	SCITRI_00481	SCITRI_00485	Phosphatidate cytidylyltransferase; Belongs to the CDS family.	Putative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	0.511
cdsA	polC	SCITRI_00481	SCITRI_00484	Phosphatidate cytidylyltransferase; Belongs to the CDS family.	DNA polymerase III subunit alpha (PolC); Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.684
cdsA	rseP	SCITRI_00481	SCITRI_00483	Phosphatidate cytidylyltransferase; Belongs to the CDS family.	Inner membrane zinc metalloprotease.	0.809
dnaE	dnaN	SCITRI_001547	SCITRI_002	DNA polymerase III subunit alpha.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.992
dnaE	dnaX	SCITRI_001547	SCITRI_007	DNA polymerase III subunit alpha.	DNA polymerase III gamma/tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.991
dnaE	holA	SCITRI_001547	SCITRI_00202	DNA polymerase III subunit alpha.	DNA polymerase III subunit delta.	0.992
dnaE	holB	SCITRI_001547	SCITRI_0010	DNA polymerase III subunit alpha.	DNA polymerase III subunit delta'.	0.986
dnaE	polA	SCITRI_001547	SCITRI_001906	DNA polymerase III subunit alpha.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.775
dnaE	polC	SCITRI_001547	SCITRI_00484	DNA polymerase III subunit alpha.	DNA polymerase III subunit alpha (PolC); Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.938
dnaN	dnaE	SCITRI_002	SCITRI_001547	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III subunit alpha.	0.992
dnaN	dnaX	SCITRI_002	SCITRI_007	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III gamma/tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.993
dnaN	holA	SCITRI_002	SCITRI_00202	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III subunit delta.	0.993
dnaN	holB	SCITRI_002	SCITRI_0010	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III subunit delta'.	0.989
dnaN	polA	SCITRI_002	SCITRI_001906	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.993
dnaN	polC	SCITRI_002	SCITRI_00484	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III subunit alpha (PolC); Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.950
dnaX	dnaE	SCITRI_007	SCITRI_001547	DNA polymerase III gamma/tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	DNA polymerase III subunit alpha.	0.991
dnaX	dnaN	SCITRI_007	SCITRI_002	DNA polymerase III gamma/tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.993
dnaX	holA	SCITRI_007	SCITRI_00202	DNA polymerase III gamma/tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	DNA polymerase III subunit delta.	0.989
dnaX	holB	SCITRI_007	SCITRI_0010	DNA polymerase III gamma/tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	DNA polymerase III subunit delta'.	0.974
dnaX	polA	SCITRI_007	SCITRI_001906	DNA polymerase III gamma/tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.489