node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APE74433.1 | rluB | SCITRI_00534 | SCITRI_00532 | Putative transposase. | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. | 0.497 |
APE74433.1 | scpA | SCITRI_00534 | SCITRI_00530 | Putative transposase. | Chromosome segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.497 |
APE74433.1 | scpB | SCITRI_00534 | SCITRI_00531 | Putative transposase. | Chromosome segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.498 |
APE74433.1 | yaaF | SCITRI_00534 | SCITRI_00533 | Putative transposase. | Deoxynucleoside kinase. | 0.522 |
deoA | dfrA | SCITRI_00529 | SCITRI_00527 | Pyrimidine-nucleoside phosphorylase. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.728 |
deoA | era | SCITRI_00529 | SCITRI_00485 | Pyrimidine-nucleoside phosphorylase. | Putative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.418 |
deoA | plsC | SCITRI_00529 | SCITRI_00528 | Pyrimidine-nucleoside phosphorylase. | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 0.929 |
deoA | rluB | SCITRI_00529 | SCITRI_00532 | Pyrimidine-nucleoside phosphorylase. | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. | 0.579 |
deoA | scpA | SCITRI_00529 | SCITRI_00530 | Pyrimidine-nucleoside phosphorylase. | Chromosome segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.579 |
deoA | scpB | SCITRI_00529 | SCITRI_00531 | Pyrimidine-nucleoside phosphorylase. | Chromosome segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.579 |
deoA | thyA | SCITRI_00529 | SCITRI_00526 | Pyrimidine-nucleoside phosphorylase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.954 |
deoA | yaaF | SCITRI_00529 | SCITRI_00533 | Pyrimidine-nucleoside phosphorylase. | Deoxynucleoside kinase. | 0.544 |
dfrA | deoA | SCITRI_00527 | SCITRI_00529 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Pyrimidine-nucleoside phosphorylase. | 0.728 |
dfrA | plsC | SCITRI_00527 | SCITRI_00528 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 0.872 |
dfrA | rluB | SCITRI_00527 | SCITRI_00532 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. | 0.505 |
dfrA | scpA | SCITRI_00527 | SCITRI_00530 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Chromosome segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.638 |
dfrA | scpB | SCITRI_00527 | SCITRI_00531 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Chromosome segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.579 |
dfrA | thyA | SCITRI_00527 | SCITRI_00526 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.991 |
dfrA | yaaF | SCITRI_00527 | SCITRI_00533 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Deoxynucleoside kinase. | 0.549 |
era | deoA | SCITRI_00485 | SCITRI_00529 | Putative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Pyrimidine-nucleoside phosphorylase. | 0.418 |