STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APE74644.1Hypothetical protein. (54 aa)    
Predicted Functional Partners:
yloP
Serine/threonine protein kinase.
  
 
 0.815
lpdA
Pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase) component.
  
 0.811
APE74645.1
Hypothetical protein.
       0.773
APE74646.1
Hypothetical protein.
       0.594
pdhB
Pyruvate dehydrogenase E1 component subunit beta.
   
  0.589
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
   0.573
APE74024.1
Hypothetical protein.
   
  0.463
APE74310.1
Putative dihydrolipoamide acetyltransferase.
   
  0.463
pdhC
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
   
  0.463
APE74820.1
Hypothetical protein.
  
 
 0.459
Your Current Organism:
Spiroplasma citri
NCBI taxonomy Id: 2133
Other names: ATCC 27556, NCPPB 2647, S. citri
Server load: low (24%) [HD]