Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ruvBHolliday junction DNA helicase RuvB. (106 aa)    
Predicted Functional Partners:
ruvA
Holliday junction DNA helicase RuvA.
  
 
 0.997
recA
Recombinase A.
  
  
 0.733
rpsR
30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
     
 0.662
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.651
recO
DNA repair protein recO.
  
  
 0.647
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
     
 0.618
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.595
APE75465.1
PTS system, fructose-specific IIABC components.
     
 0.563
cinA
Putative competence-damage inducible protein; Belongs to the CinA family.
  
  
 0.554
celB
PTS system cellobiose-specific component IIC.
      
 0.540
Your Current Organism:
Spiroplasma citri
NCBI taxonomy Id: 2133
Other names: ATCC 27556, NCPPB 2647, S. citri
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