apt protein (Spiroplasma citri) - STRING interaction network

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apt

Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa)

Predicted Functional Partners:

purB

0.975

adk

0.948

deoD

0.918

guaA

0.795

purA

0.764

secDF

0.748

relA

0.708

gmk

0.611

hprT

0.536

APE74677.1

0.511

Your Current Organism:

Spiroplasma citri

NCBI taxonomy Id: 2133
Other names: ATCC 27556, NCPPB 2647, S. citri

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APE74677.1	apt	SCITRI_00784	SCITRI_00786	Hypothetical protein.	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.511
APE74677.1	relA	SCITRI_00784	SCITRI_00787	Hypothetical protein.	GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the degradation of ppGpp into GDP. It may also be capable of catalyzing the synthesis of ppGpp (By similarity); Belongs to the RelA/SpoT family.	0.415
APE74677.1	secDF	SCITRI_00784	SCITRI_00785	Hypothetical protein.	Bifunctional preprotein translocase subunit SecD/SecF.	0.568
adk	apt	SCITRI_00351	SCITRI_00786	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.948
adk	gmk	SCITRI_00351	SCITRI_00446	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.760
adk	guaA	SCITRI_00351	SCITRI_00386	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.602
adk	hprT	SCITRI_00351	SCITRI_00385	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.930
adk	purA	SCITRI_00351	SCITRI_00274	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.409
adk	purB	SCITRI_00351	SCITRI_00275	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Adenylosuccinate lyase.	0.950
apt	APE74677.1	SCITRI_00786	SCITRI_00784	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Hypothetical protein.	0.511
apt	adk	SCITRI_00786	SCITRI_00351	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.948
apt	deoD	SCITRI_00786	SCITRI_00597	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Purine nucleoside phosphorylase.	0.918
apt	gmk	SCITRI_00786	SCITRI_00446	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.611
apt	guaA	SCITRI_00786	SCITRI_00386	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.795
apt	hprT	SCITRI_00786	SCITRI_00385	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.536
apt	purA	SCITRI_00786	SCITRI_00274	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.764
apt	purB	SCITRI_00786	SCITRI_00275	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Adenylosuccinate lyase.	0.975
apt	relA	SCITRI_00786	SCITRI_00787	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the degradation of ppGpp into GDP. It may also be capable of catalyzing the synthesis of ppGpp (By similarity); Belongs to the RelA/SpoT family.	0.708
apt	secDF	SCITRI_00786	SCITRI_00785	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Bifunctional preprotein translocase subunit SecD/SecF.	0.748
deoD	apt	SCITRI_00597	SCITRI_00786	Purine nucleoside phosphorylase.	Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.918

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