STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APE74825.1Hypothetical protein. (249 aa)    
Predicted Functional Partners:
yloP
Serine/threonine protein kinase.
  
 
 0.815
lpdA
Pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase) component.
  
 0.811
pdhB
Pyruvate dehydrogenase E1 component subunit beta.
   
  0.589
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
   0.573
APE74824.1
Hypothetical protein.
       0.477
APE74024.1
Hypothetical protein.
   
  0.463
APE74310.1
Putative dihydrolipoamide acetyltransferase.
   
  0.463
pdhC
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
   
  0.463
APE74820.1
Hypothetical protein.
  
 
 0.459
prs
Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
  0.458
Your Current Organism:
Spiroplasma citri
NCBI taxonomy Id: 2133
Other names: ATCC 27556, NCPPB 2647, S. citri
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.