| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AIA73708.1 | AIA74203.1 | FF32_02285 | FF32_04905 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.978 |
| AIA73708.1 | AIA75286.1 | FF32_02285 | FF32_10635 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.943 |
| AIA73708.1 | AIA75393.1 | FF32_02285 | FF32_11185 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.948 |
| AIA73708.1 | AIA75395.1 | FF32_02285 | FF32_11195 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.991 |
| AIA73708.1 | AIA75557.1 | FF32_02285 | FF32_12100 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.965 |
| AIA73708.1 | AIA76026.1 | FF32_02285 | FF32_14610 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.968 |
| AIA73708.1 | AIA76334.1 | FF32_02285 | FF32_16260 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.937 |
| AIA73708.1 | aceE | FF32_02285 | FF32_12770 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.995 |
| AIA73708.1 | gltA | FF32_02285 | FF32_11160 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.965 |
| AIA73708.1 | sucC | FF32_02285 | FF32_11200 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.947 |
| AIA74203.1 | AIA73708.1 | FF32_04905 | FF32_02285 | Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.978 |
| AIA74203.1 | AIA75393.1 | FF32_04905 | FF32_11185 | Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.975 |
| AIA74203.1 | AIA75395.1 | FF32_04905 | FF32_11195 | Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.924 |
| AIA74203.1 | AIA75557.1 | FF32_04905 | FF32_12100 | Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.430 |
| AIA74203.1 | AIA76026.1 | FF32_04905 | FF32_14610 | Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.986 |
| AIA74203.1 | aceE | FF32_04905 | FF32_12770 | Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.975 |
| AIA74203.1 | gltA | FF32_04905 | FF32_11160 | Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.430 |
| AIA74203.1 | sucC | FF32_04905 | FF32_11200 | Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.554 |
| AIA75286.1 | AIA73708.1 | FF32_10635 | FF32_02285 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.943 |
| AIA75286.1 | AIA75393.1 | FF32_10635 | FF32_11185 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 2-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.498 |
