Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AIA73734.1Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (342 aa)    
Predicted Functional Partners:
AIA73710.1
Nicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family.
 
 
 0.999
AIA75567.1
L-aspartate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
    0.803
AIA76349.1
Sugar transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.696
AIA75044.1
Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.667
birA
biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.657
AIA76537.1
Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.642
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.614
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
  
  
 0.564
AIA75844.1
Nicotinate-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.559
Your Current Organism:
Halomonas campaniensis
NCBI taxonomy Id: 213554
Other names: ATCC BAA-966, DSM 15293, H. campaniensis, Halomonas campaniae, Halomonas campaniensis Romano et al. 2005, Halomonas campisalis subsp. campaniae, strain 5AG
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