Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AIA74150.1MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)    
Predicted Functional Partners:
AIA74165.1
4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.631
AIA74156.1
Maleylacetoacetate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.588
AIA74149.1
C4-dicarboxylate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.585
AIA74148.1
C4-dicarboxylate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.563
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
   
 0.538
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
  
 0.513
glnS
glutamate--tRNA ligase; Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.500
AIA74152.1
FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.497
AIA74153.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.491
AIA74155.1
2-keto-4-pentenoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.483
Your Current Organism:
Halomonas campaniensis
NCBI taxonomy Id: 213554
Other names: ATCC BAA-966, DSM 15293, H. campaniensis, Halomonas campaniae, Halomonas campaniensis Romano et al. 2005, Halomonas campisalis subsp. campaniae, strain 5AG
Server load: low (26%) [HD]