Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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[Homology]
Score
AIA74155.12-keto-4-pentenoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)    
Predicted Functional Partners:
AIA74156.1
Maleylacetoacetate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.996
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
  
 0.938
AIA74165.1
4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.897
sdhA
Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
  0.823
aspA
Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
  0.822
sdhB
Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.814
AIA75390.1
Succinate dehydrogenase; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
   
 
  0.807
AIA75389.1
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.806
AIA76168.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.802
AIA74152.1
FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.694
Your Current Organism:
Halomonas campaniensis
NCBI taxonomy Id: 213554
Other names: ATCC BAA-966, DSM 15293, H. campaniensis, Halomonas campaniae, Halomonas campaniensis Romano et al. 2005, Halomonas campisalis subsp. campaniae, strain 5AG
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