Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AIA75042.1Cysteine desulfurase; Catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)    
Predicted Functional Partners:
AIA73732.1
Recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.987
iscA
Forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family.
 
 
 0.987
AIA75612.1
Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.987
AIA75043.1
Transcriptional regulator; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
 
  
 0.984
AIA75508.1
Molybdopterin-synthase adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.981
nfuA
Amino acid ABC transporter substrate-binding protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 0.965
AIA74189.1
3-mercaptopyruvate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.921
AIA76081.1
Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.921
AIA76636.1
Thiosulfate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.921
AIA75636.1
Rrf2 family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.918
Your Current Organism:
Halomonas campaniensis
NCBI taxonomy Id: 213554
Other names: ATCC BAA-966, DSM 15293, H. campaniensis, Halomonas campaniae, Halomonas campaniensis Romano et al. 2005, Halomonas campisalis subsp. campaniae, strain 5AG
Server load: low (12%) [HD]